pH-Triggered release from surface-modified poly(lactic-co-glycolic acid) nanoparticles

pH-Triggered release from surface-modified poly(lactic-co-glycolic acid) nanoparticles

Nanoparticles (NP) of poly(lactic-co-glycolic acid) (PLGA) represent a promising biodegradable drug delivery system. We suggest here a two-step release system of PLGA nanoparticles with a pH-tunable polymeric shell, providing an initial pH-triggered step, releasing a membrane-toxic cationic compound...

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Bibliographic Details
Main Authors: Manuel Häuser, Klaus Langer, Monika Schönhoff
Format: Article
Language:English
Published: Beilstein-Institut 2015-12-01
Series:Beilstein Journal of Nanotechnology
Subjects:
layer-by-layer self-assembly
pH-triggered release
PLGA nanoparticles
polyelectrolyte multilayers
weak polyelectrolyte
Online Access:https://doi.org/10.3762/bjnano.6.260

Internet

https://doi.org/10.3762/bjnano.6.260

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