Protein production in Escherichia coli is guided by the trade-off between intracellular substrate availability and energy cost

Abstract Background In vivo protein formation is a crucial part of cellular life. The process needs to adapt to growth conditions and is exploited for the production of technical and pharmaceutical proteins in microbes such as Escherichia coli. Accordingly, the elucidation of basic regulatory mechan...

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Bibliographic Details
Main Authors: Alexander Nieß, Martin Siemann-Herzberg, Ralf Takors
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Microbial Cell Factories
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12934-019-1057-5