Use of saliva to monitor meningococcal vaccine responses: proposing a threshold in saliva as surrogate of protection

Use of saliva to monitor meningococcal vaccine responses: proposing a threshold in saliva as surrogate of protection

Abstract Background Mucosal antibodies against capsular polysaccharides offer protection against acquisition and carriage of encapsulated bacteria like Neisseria meningitidis serogroup C. Measurements of salivary antibodies as replacement for blood testing has important (cost-effective) advantages,...

Full description

Bibliographic Details
Main Authors: Mariëtte B. van Ravenhorst, Fiona R. M. van der Klis, Debbie M. van Rooijen, Elisabeth A. M. Sanders, Guy A. M. Berbers
Format: Article
Language:English
Published: BMC 2019-01-01
Series:BMC Medical Research Methodology
Subjects:
Neisseria meningitidis
Correlate of protection
Salivary surrogate of protection
Threshold
Conjugate meningococcal vaccine
Online Access:http://link.springer.com/article/10.1186/s12874-018-0650-3

Internet

http://link.springer.com/article/10.1186/s12874-018-0650-3

Similar Items