Virus-Induced Type I Interferon Deteriorates Control of Systemic Pseudomonas Aeruginosa Infection

Virus-Induced Type I Interferon Deteriorates Control of Systemic Pseudomonas Aeruginosa Infection

Background: Type I interferon (IFN-I) predisposes to bacterial superinfections, an important problem during viral infection or treatment with interferon-alpha (IFN-α). IFN-I-induced neutropenia is one reason for the impaired bacterial control; however there is evidence that more frequent bacterial i...

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Bibliographic Details
Main Authors: Katja Merches, Vishal Khairnar, Torben Knuschke, Namir Shaabani, Nadine Honke, Vikas Duhan, Mike Recher, Alexander A. Navarini, Cornelia Hardt, Dieter Häussinger, Burkhard Tümmler, Erich Gulbins, Anthony H. Futerman, Daniel Hoffmann, Florian Lang, Philipp A. Lang, Astrid M. Westendorf, Karl S. Lang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-07-01
Series:Cellular Physiology and Biochemistry
Subjects:
Lysozyme
Pseudomonas aeruginosa
Type I interferon
LCMV
Bacterial superinfection
Online Access:http://www.karger.com/Article/FullText/430200

Internet

http://www.karger.com/Article/FullText/430200

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