Efficiency of Xist-mediated silencing on autosomes is linked to chromosomal domain organisation
<p>Abstract</p> <p>Background</p> <p>X chromosome inactivation, the mechanism used by mammals to equalise dosage of X-linked genes in XX females relative to XY males, is triggered by chromosome-wide localisation of a <it>cis</it>-acting non-coding RNA, Xist....
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2010-05-01
|
| Series: | Epigenetics & Chromatin |
| Online Access: | http://www.epigeneticsandchromatin.com/content/3/1/10 |