MiR-219-5p suppresses cell proliferation and cell cycle progression in esophageal squamous cell carcinoma by targeting CCNA2

MiR-219-5p suppresses cell proliferation and cell cycle progression in esophageal squamous cell carcinoma by targeting CCNA2

Abstract Background We investigated the potential regulatory role of miR-219-5p in esophageal squamous cell carcinoma (ESCC) and looked at the underlying mechanisms in ESCC. Methods Real-time PCR was used to determine the levels of miR-219-5p in ESCC tissues and cell lines. The effects of miR-219-5p...

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Bibliographic Details
Main Author: Qiang Ma
Format: Article
Language:English
Published: BMC 2019-02-01
Series:Cellular & Molecular Biology Letters
Subjects:
Esophageal squamous cell carcinoma
miR-219-5p
CCNA2
Cell proliferation
G2/M phase arrest
Online Access:http://link.springer.com/article/10.1186/s11658-018-0129-6

Internet

http://link.springer.com/article/10.1186/s11658-018-0129-6

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