Supplementation of Adult Rats with Moderate Amounts of β-Carotene Modulates the Redox Status in Plasma without Exerting Pro-Oxidant Effects in the Brain: A Safer Alternative to Food Fortification with Vitamin A?

Supplementation of Adult Rats with Moderate Amounts of β-Carotene Modulates the Redox Status in Plasma without Exerting Pro-Oxidant Effects in the Brain: A Safer Alternative to Food Fortification with Vitamin A?

Despite the antioxidant potential of vitamin A, recent studies reported that chronic retinol ester supplementation can also exert pro-oxidant effects and neurotoxicity in vivo and raises the mortality rates among healthy subjects. Our aim was to find evidence for a safer (i.e., less toxic) molecule...

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Bibliographic Details
Main Authors: Carlos Eduardo Schnorr, Maurilio da Silva Morrone, André Simões-Pires, Leonardo da Silva Bittencourt, Fares Zeidán-Chuliá, José Cláudio Fonseca Moreira
Format: Article
Language:English
Published: MDPI AG 2014-12-01
Series:Nutrients
Subjects:
vitamin A
rat model
oxidative stress
retinol
toxicity
nutrition
Online Access:http://www.mdpi.com/2072-6643/6/12/5572

Internet

http://www.mdpi.com/2072-6643/6/12/5572

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