HIF-α/MIF and NF-κB/IL-6 Axes Contribute to the Recruitment of CD11b+Gr-1+ Myeloid Cells in Hypoxic Microenvironment of HNSCC

CD11b+Gr-1+ myeloid cells have gained much attention due to their roles in tumor immunity suppression as well as promotion of angiogenesis, invasion, and metastases. However, the mechanisms by which CD11b+Gr-1+ myeloid cells recruit to the tumor site have not been well clarified. In the present stu...

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Bibliographic Details
Main Authors: Guiquan Zhu, Yaling Tang, Ning Geng, Min Zheng, Jian Jiang, Ling Li, Kaide Li, Zhengge Lei, Wei Chen, Yunlong Fan, Xiangrui Ma, Longjiang Li, Xiaoyi Wang, Xinhua Liang
Format: Article
Language:English
Published: Elsevier 2014-02-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S147655861480016X