Vascular endothelial growth factor regulates osteoblast survival – evidence for an autocrine feedback mechanism

<p>Abstract</p> <p>Background</p> <p>Apoptosis of osteoblasts and osteoclasts regulates bone homeostasis. Skeletal injury in humans results in 'angiogenic' responses primarily mediated by vascular endothelial growth factor(VEGF), a protein essential for bone r...

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Bibliographic Details
Main Authors: Street John, Lenehan Brian
Format: Article
Language:English
Published: BMC 2009-06-01
Series:Journal of Orthopaedic Surgery and Research
Online Access:http://www.josr-online.com/content/4/1/19