Unique true predicted neoantigens (TPNAs) correlates with anti-tumor immune control in HCC patients

Unique true predicted neoantigens (TPNAs) correlates with anti-tumor immune control in HCC patients

Abstract Background A novel prediction algorithm is needed for the identification of effective tumor associated mutated neoantigens. Only those with no homology to self wild type antigens are true predicted neoantigens (TPNAs) and can elicit an antitumor T cell response, not attenuated by central to...

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Bibliographic Details
Main Authors: Annacarmen Petrizzo, Maria Tagliamonte, Angela Mauriello, Valerio Costa, Marianna Aprile, Roberta Esposito, Andrea Caporale, Antonio Luciano, Claudio Arra, Maria Lina Tornesello, Franco M. Buonaguro, Luigi Buonaguro
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Journal of Translational Medicine
Subjects:
Liver cancer
Immunotherapy
Cancer vaccine
Personalized treatment
Neoantigens
Online Access:http://link.springer.com/article/10.1186/s12967-018-1662-9

Internet

http://link.springer.com/article/10.1186/s12967-018-1662-9

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