Long non-coding RNA cancer susceptibility candidate 2 (CASC2) alleviates the high glucose-induced injury of CIHP-1 cells via regulating miR-9-5p/PPARγ axis in diabetes nephropathy

Long non-coding RNA cancer susceptibility candidate 2 (CASC2) alleviates the high glucose-induced injury of CIHP-1 cells via regulating miR-9-5p/PPARγ axis in diabetes nephropathy

Abstract Background High glucose (HG) induced podocytes injury plays an important role in diabetes nephropathy (DN) development. Long noncoding RNA cancer susceptibility candidate 2 (CASC2) was found to be decreased in serum of DN patients. We aimed to explore the function and possible mechanism of...

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Bibliographic Details
Main Authors: Feng Li, Bo Dai, Xiquan Ni
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Diabetology & Metabolic Syndrome
Subjects:
High glucose
Podocyte
CASC2
miR-9-5p
PPARγ
Online Access:http://link.springer.com/article/10.1186/s13098-020-00574-8

Internet

http://link.springer.com/article/10.1186/s13098-020-00574-8

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