Increased expression of CDKN1A/p21 in HIV-1 controllers is correlated with upregulation of ZC3H12A/MCPIP1

Increased expression of CDKN1A/p21 in HIV-1 controllers is correlated with upregulation of ZC3H12A/MCPIP1

Abstract Background Some multifunctional cellular proteins, as the monocyte chemotactic protein-induced protein 1 (ZC3H12A/MCPIP1) and the cyclin-dependent kinase inhibitor CDKN1A/p21, are able to modulate the cellular susceptibility to the human immunodeficiency virus type 1 (HIV-1). Several studie...

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Bibliographic Details
Main Authors: Suwellen S. D. de Azevedo, Marcelo Ribeiro-Alves, Fernanda H. Côrtes, Edson Delatorre, Lucia Spangenberg, Hugo Naya, Leonardo N. Seito, Brenda Hoagland, Beatriz Grinsztejn, Valdilea G. Veloso, Mariza G. Morgado, Thiago Moreno L. Souza, Gonzalo Bello
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Retrovirology
Subjects:
HIV-1 controllers
Restriction factors
MCPIP1
p21
Immune activation
Online Access:http://link.springer.com/article/10.1186/s12977-020-00522-4

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http://link.springer.com/article/10.1186/s12977-020-00522-4

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