Mutational Evolution in Relapsed Diffuse Large B-Cell Lymphoma

Mutational Evolution in Relapsed Diffuse Large B-Cell Lymphoma

Current genomic models in diffuse large B-cell lymphoma (DLBCL) are based on single tumor biopsies, which might underestimate heterogeneity. Data on mutational evolution largely remains unknown. An exploratory study using whole exome sequencing on paired (primary and relapse) formalin fixed paraffin...

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Bibliographic Details
Main Authors: Marcel Nijland, Annika Seitz, Martijn Terpstra, Gustaaf W. van Imhoff, Philip M Kluin, Tom van Meerten, Çiğdem Atayar, Léon C. van Kempen, Arjan Diepstra, Klaas Kok, Anke van den Berg
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:Cancers
Subjects:
diffuse large B-cell lymphoma
relapse
mutations
heterogeneity
evolution
fresh frozen paraffin embedded
Online Access:https://www.mdpi.com/2072-6694/10/11/459

Internet

https://www.mdpi.com/2072-6694/10/11/459

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