Significant transcriptomic changes are associated with differentiation of bone marrow-derived mesenchymal stem cells into neural progenitor-like cells in the presence of bFGF and EGF

Significant transcriptomic changes are associated with differentiation of bone marrow-derived mesenchymal stem cells into neural progenitor-like cells in the presence of bFGF and EGF

Abstract Introduction Mesenchymal stem cells (MSCs) isolated from bone marrow have different developmental origins, including neural crest. MSCs can differentiate into neural progenitor-like cells (NPCs) under the influence of bFGF and EGF. NPCs can terminally differentiate into neurons that express...

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Bibliographic Details
Main Authors: Amir Ali Khan, Tee Jong Huat, Abdullah Al Mutery, Ahmed Taher El-Serafi, Hassen Hadj Kacem, Sallam Hasan Abdallah, Muhammed Faruque Reza, Jafri Malin Abdullah, Hasnan Jaafar
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Cell & Bioscience
Subjects:
Mesenchymal stem cells
Neural progenitor-like cells
Differentiation
mRNA-seq
EGF
bFGF
Online Access:http://link.springer.com/article/10.1186/s13578-020-00487-z

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http://link.springer.com/article/10.1186/s13578-020-00487-z

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