Anticancer Effect of Fucoidan on DU-145 Prostate Cancer Cells through Inhibition of PI3K/Akt and MAPK Pathway Expression

In this study, we showed that PI3K/Akt signaling mediates fucoidan’s anticancer effects on prostate cancer cells, including suppression of proliferation. Fucoidan significantly decreased viability of DU-145 cancer cells in a concentration-dependent manner as shown by MTT [3-(4,5-dimethylthiazol-2-yl...

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Bibliographic Details
Main Authors: Gang-Sik Choo, Hae-Nim Lee, Seong-Ah Shin, Hyeong-Jin Kim, Ji-Youn Jung
Format: Article
Language:English
Published: MDPI AG 2016-07-01
Series:Marine Drugs
Subjects:
Akt
Online Access:http://www.mdpi.com/1660-3397/14/7/126