Buffering the pH of the culture medium does not extend yeast replicative lifespan [v1; ref status: indexed, http://f1000r.es/20w]

Buffering the pH of the culture medium does not extend yeast replicative lifespan [v1; ref status: indexed, http://f1000r.es/20w]

During chronological aging of budding yeast cells, the culture medium can become acidified, and this acidification limits cell survival.  As a consequence, buffering the culture medium to pH 6 significantly extends chronological life span under standard conditions in synthetic medium.  In this study...

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Bibliographic Details
Main Authors: Brian M Wasko, Daniel T Carr, Herman Tung, Ha Doan, Nathan Schurman, Jillian R Neault, Joey Feng, Janet Lee, Ben Zipkin, Jacob Mouser, Edward Oudanonh, Tina Nguyen, Torin Stetina, Anna Shemorry, Mekedes Lemma, Matt Kaeberlein
Format: Article
Language:English
Published: F1000 Research Ltd 2013-10-01
Series:F1000Research
Subjects:
Microbial Growth & Development
Microbial Physiology & Metabolism
Online Access:http://f1000research.com/articles/2-216/v1

Internet

http://f1000research.com/articles/2-216/v1

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