N-Palmitoylethanolamine-oxazoline (PEA-OXA): A new therapeutic strategy to reduce neuroinflammation, oxidative stress associated to vascular dementia in an experimental model of repeated bilateral common carotid arteries occlusion

N-Palmitoylethanolamine-oxazoline (PEA-OXA): A new therapeutic strategy to reduce neuroinflammation, oxidative stress associated to vascular dementia in an experimental model of repeated bilateral common carotid arteries occlusion

Aim: Recent studies revealed that pharmacological modulation of NAE-hydrolyzing acid amidase (NAAA) can be achieved with PEA oxazoline (PEA-OXA). Hence, the aim of the present work was to thoroughly evaluate the anti-inflammatory and neuroprotective effects of PEA-OXA in an experimental model of vas...

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Bibliographic Details
Main Authors: Daniela Impellizzeri, Rosalba Siracusa, Marika Cordaro, Rosalia Crupi, Alessio Filippo Peritore, Enrico Gugliandolo, Ramona D'Amico, Stefania Petrosino, Maurizio Evangelista, Rosanna Di Paola, Salvatore Cuzzocrea
Format: Article
Language:English
Published: Elsevier 2019-05-01
Series:Neurobiology of Disease
Subjects:
Neuroprotection
Palmitoylethanolamide
Oxazoline
Oxidative stress
Inflammation
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996118305382

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http://www.sciencedirect.com/science/article/pii/S0969996118305382

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