Surface-layer protein A (SlpA) is a major contributor to host-cell adherence of Clostridium difficile.

Clostridium difficile is a leading cause of antibiotic-associated diarrhea, and a significant etiologic agent of healthcare-associated infections. The mechanisms of attachment and host colonization of C. difficile are not well defined. We hypothesize that non-toxin bacterial factors, especially thos...

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Bibliographic Details
Main Authors: Michelle M Merrigan, Anilrudh Venugopal, Jennifer L Roxas, Farhan Anwar, Michael J Mallozzi, Bryan A P Roxas, Dale N Gerding, V K Viswanathan, Gayatri Vedantam
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3827033?pdf=render