Inhibition of the key metabolic pathways, glycolysis and lipogenesis, of oral cancer by bitter melon extract

Inhibition of the key metabolic pathways, glycolysis and lipogenesis, of oral cancer by bitter melon extract

Abstract Background Metabolic reprogramming is one of the hallmarks of cancer which favours rapid energy production, biosynthetic capabilities and therapy resistance. In our previous study, we showed bitter melon extract (BME) prevents carcinogen induced mouse oral cancer. RNA sequence analysis from...

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Bibliographic Details
Main Authors: Subhayan Sur, Hiroshi Nakanishi, Colin Flaveny, Joseph E. Ippolito, Jane McHowat, David A. Ford, Ratna B. Ray
Format: Article
Language:English
Published: BMC 2019-10-01
Series:Cell Communication and Signaling
Subjects:
Bitter melon extract
Oral cancer
Glycolysis
Lipid metabolism
Phosphatidylcholine
Phosphatidylethanolamine
Online Access:http://link.springer.com/article/10.1186/s12964-019-0447-y

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http://link.springer.com/article/10.1186/s12964-019-0447-y

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