Identification and Characterization of Cannabimovone, a Cannabinoid from <i>Cannabis sativa</i>, as a Novel PPARγ Agonist via a Combined Computational and Functional Study

Identification and Characterization of Cannabimovone, a Cannabinoid from <i>Cannabis sativa</i>, as a Novel PPARγ Agonist via a Combined Computational and Functional Study

Phytocannabinoids (pCBs) are a large family of meroterpenoids isolated from the plant <i>Cannabis sativa</i>. &#916;<sup>9</sup>-Tetrahydrocannabinol (THC) and cannabidiol (CBD) are the best investigated phytocannabinoids due to their relative abundance and interesting bi...

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Bibliographic Details
Main Authors: Fabio Arturo Iannotti, Fabrizia De Maio, Elisabetta Panza, Giovanni Appendino, Orazio Taglialatela-Scafati, Luciano De Petrocellis, Pietro Amodeo, Rosa Maria Vitale
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Molecules
Subjects:
phytocannabinoids
cannabimovone (cbm)
peroxisome proliferator-activated receptor gamma (pparγ)
molecular docking
molecular dynamics
insulin resistance
Online Access:https://www.mdpi.com/1420-3049/25/5/1119

Internet

https://www.mdpi.com/1420-3049/25/5/1119

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