Development of an all-in-one lentiviral vector system based on the original TetR for the easy generation of Tet-ON cell lines.

Lentiviral vectors (LVs) are considered one of the most promising vehicles to efficiently deliver genetic information for basic research and gene therapy approaches. Combining LVs with drug-inducible expression systems should allow tight control of transgene expression with minimal side effect on re...

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Bibliographic Details
Main Authors: Karim Benabdellah, Marién Cobo, Pilar Muñoz, Miguel G Toscano, Francisco Martin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3158098?pdf=render