Circuit-specific hippocampal ΔFosB underlies resilience to stress-induced social avoidance

Circuit-specific hippocampal ΔFosB underlies resilience to stress-induced social avoidance

Chronic stress is a risk factor for mood disorders, yet the molecular and circuit mechanisms of stress-induced changes are not well understood. Here, the authors report the role of the transcription factor ΔFosB in driving activity changes in response to stress in glutamatergic neurons in the ventra...

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Bibliographic Details
Main Authors: Andrew L. Eagle, Claire E. Manning, Elizabeth S. Williams, Ryan M. Bastle, Paula A. Gajewski, Amber Garrison, Alexis J. Wirtz, Seda Akguen, Katie Brandel-Ankrapp, Wilson Endege, Frederick M. Boyce, Yoshinori N. Ohnishi, Michelle Mazei-Robison, Ian Maze, Rachel L. Neve, Alfred J. Robison
Format: Article
Language:English
Published: Nature Publishing Group 2020-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-17825-x

Internet

https://doi.org/10.1038/s41467-020-17825-x

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