Circulating Reactive Oxidant Causes Apoptosis of Retinal Pigment Epithelium and Cone Photoreceptors in the Mouse Central Retina

Reactive oxidants damage the retinal pigment epithelium (RPE), which is required for viability of overlying photoreceptors. Smoking which leads to chronic accumulation of reactive oxidants in the circulation is linked to age-related macular degeneration (AMD) where RPE death is seen along with photo...

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Bibliographic Details
Main Authors: Wei Wang, Jennifer Noel, Henry J. Kaplan, Douglas C. Dean
Format: Article
Language:English
Published: SAGE Publishing 2011-01-01
Series:Ophthalmology and Eye Diseases
Online Access:https://doi.org/10.4137/OED.S7797