In silico design of hydrazone antioxidants and analysis of their free radical-scavenging mechanism by thermodynamic studies

In silico design of hydrazone antioxidants and analysis of their free radical-scavenging mechanism by thermodynamic studies

Abstract Background Antioxidants are very crucial in maintaining the normal function of body cells, as they scavenge excess free radical in the body. A set of hydrazone antioxidants was designed by in silico screening. The density functional theory (DFT) method was employed to explore the reaction e...

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Bibliographic Details
Main Authors: Ikechukwu Ogadimma Alisi, Adamu Uzairu, Stephen Eyije Abechi
Format: Article
Language:English
Published: SpringerOpen 2019-10-01
Series:Beni-Suef University Journal of Basic and Applied Sciences
Subjects:
Hydrazone
Free radical
Antioxidant
Scavenging mechanism
In silico design
Online Access:http://link.springer.com/article/10.1186/s43088-019-0011-2

Internet

http://link.springer.com/article/10.1186/s43088-019-0011-2

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