Photodynamic priming with triple-receptor targeted nanoconjugates that trigger T cell-mediated immune responses in a 3D in vitro heterocellular model of pancreatic cancer

Photodynamic priming with triple-receptor targeted nanoconjugates that trigger T cell-mediated immune responses in a 3D in vitro heterocellular model of pancreatic cancer

Photodynamic priming (PDP), a collateral effect of photodynamic therapy, can transiently alter the tumor microenvironment (TME) beyond the cytotoxic zone. Studies have demonstrated that PDP increases tumor permeability and modulates immune-stimulatory effects by inducing immunogenic cell death, via...

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Bibliographic Details
Main Authors: De Silva Pushpamali, Bano Shazia, Pogue Brian W., Wang Kenneth K., Maytin Edward V., Hasan Tayyaba
Format: Article
Language:English
Published: De Gruyter 2021-08-01
Series:Nanophotonics
Subjects:
immunogenic cell death
multitargeting
photodynamic therapy
photoimmuno-nano-conjugates
t cell priming
tumor heterogeneity
Online Access:https://doi.org/10.1515/nanoph-2021-0304

Internet

https://doi.org/10.1515/nanoph-2021-0304

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