Cancerous phenotypes associated with hypoxia-inducible factors are not influenced by the volatile anesthetic isoflurane in renal cell carcinoma.

The possibility that anesthesia during cancer surgery may affect cancer recurrence, metastasis, and patient prognosis has become one of the most important topics of interest in cancer treatment. For example, the volatile anesthetic isoflurane was reported in several studies to induce hypoxia-inducib...

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Bibliographic Details
Main Authors: Chisato Sumi, Yoshiyuki Matsuo, Munenori Kusunoki, Tomohiro Shoji, Takeo Uba, Teppei Iwai, Hidemasa Bono, Kiichi Hirota
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0215072