Evolutionary analysis of functional divergence among chemokine receptors, decoy receptors and viral receptors

Chemokine receptors (CKRs) function in the inflammatory response and in vertebrate homeostasis. Decoy and viral receptors are two types of CKR homologues with modified functions from those of the typical CKRs. The decoy receptors are able to bind ligands without signaling. On the other hand, the vir...

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Bibliographic Details
Main Authors: Hiromi eDaiyasu, Wataru eNemoto, Hiroyuki eToh
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-07-01
Series:Frontiers in Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2012.00264/full