Marked regional endothelial dysfunction in mottled skin area in patients with severe infections

Abstract Background Mottling around the knee, reflecting a reduced skin blood flow, is predictive of mortality in patients with septic shock. However, the causative pathophysiology of mottling remains unknown. We hypothesized that the cutaneous hypoperfusion observed in the mottled area is related t...

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Bibliographic Details
Main Authors: Simon Bourcier, Jérémie Joffre, Vincent Dubée, Gabriel Preda, Jean-Luc Baudel, Naïke Bigé, Guillaume Leblanc, Bernard I. Levy, Bertrand Guidet, Eric Maury, Hafid Ait-Oufella
Format: Article
Language:English
Published: BMC 2017-06-01
Series:Critical Care
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13054-017-1742-x