Increased Susceptibility of Humanized NSG Mice to Panton-Valentine Leukocidin and Staphylococcus aureus Skin Infection.

Increased Susceptibility of Humanized NSG Mice to Panton-Valentine Leukocidin and Staphylococcus aureus Skin Infection.

Staphylococcus aureus is a leading cause of skin and soft-tissue infections worldwide. Mice are the most commonly used animals for modeling human staphylococcal infections. However a supra-physiologic S. aureus inoculum is required to establish gross murine skin pathology. Moreover, many staphylococ...

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Bibliographic Details
Main Authors: Ching Wen Tseng, Juan Carlos Biancotti, Bethany L Berg, David Gate, Stacey L Kolar, Sabrina Müller, Maria D Rodriguez, Kavon Rezai-Zadeh, Xuemo Fan, David O Beenhouwer, Terrence Town, George Y Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1005292

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https://doi.org/10.1371/journal.ppat.1005292

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