The γ-tubulin meshwork assists in the recruitment of PCNA to chromatin in mammalian cells

Corvaisier et al discover that γ-tubulin and replication protein PCNA forms a complex and that this facilitates recruitment of PCNA to chromatin both during cell division and during the DSB repair response. They identify a PCNA binding motif in γ-tubulin, which when mutated affects replication fork...

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Bibliographic Details
Main Authors: Matthieu Corvaisier, Jingkai Zhou, Darina Malycheva, Nicola Cornella, Dimitrios Chioureas, Nina M. S. Gustafsson, Catalina Ana Rosselló, Silvia Ayora, Tongbin Li, Kristina Ekström-Holka, Karin Jirström, Lisa Lindström, Maria Alvarado-Kristensson
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-02280-1