Transverse sinus injections drive robust whole-brain expression of transgenes

Convenient, efficient and fast whole-brain delivery of transgenes presents a persistent experimental challenge in neuroscience. Recent advances demonstrate whole-brain gene delivery by retro-orbital injection of virus, but slow and sparse expression and the large injection volumes required make this...

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Bibliographic Details
Main Authors: Ali S Hamodi, Aude Martinez Sabino, N Dalton Fitzgerald, Dionysia Moschou, Michael C Crair
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-05-01
Series:eLife
Subjects:
rat
Online Access:https://elifesciences.org/articles/53639