Ares-GT: Design of guide RNAs targeting multiple genes for CRISPR-Cas experiments.

Guide RNA design for CRISPR genome editing of gene families is a challenging task as usually good candidate sgRNAs are tagged with low scores precisely because they match several locations in the genome, thus time-consuming manual evaluation of targets is required. To address this issues, I have dev...

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Bibliographic Details
Main Author: Eugenio Gómez Minguet
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0241001