High Doses of Bupleurum falcatum Partially Prevents Estrogen Deficiency-Induced Bone Loss With Anti-osteoclastogenic Activity Due to Enhanced iNOS/NO Signaling

High Doses of Bupleurum falcatum Partially Prevents Estrogen Deficiency-Induced Bone Loss With Anti-osteoclastogenic Activity Due to Enhanced iNOS/NO Signaling

Background and Objective:Bupleurum falcatum (BF) extract, a natural product with anti-inflammatory properties, has been traditionally used to treat menopausal symptoms, but its role in osteoporosis, another serious health concern of menopausal women, remains unknown. Here we investigated whether and...

Full description

Bibliographic Details
Main Authors: Mijung Yeom, Eun-Young Kim, Jae-Hyun Kim, Hyuk-Sang Jung, Youngjoo Sohn
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Pharmacology
Subjects:
Bupleurum falcatum
postmenopausal osteoporosis
bone resorption
osteoclasts
ovariectomized rats
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.01314/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2018.01314/full

Similar Items