Regulation of cardiomyocyte fate plasticity: a key strategy for cardiac regeneration

Abstract With the high morbidity and mortality rates, cardiovascular diseases have become one of the most concerning diseases worldwide. The heart of adult mammals can hardly regenerate naturally after injury because adult cardiomyocytes have already exited the cell cycle, which subseqently triggers...

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Bibliographic Details
Main Authors: Rui Gong, Zuke Jiang, Naufal Zagidullin, Tianyi Liu, Benzhi Cai
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-020-00413-2