New Insights Into The Generation Of CD4 Memory May Shape Future Vaccine Strategies For Influenza

New Insights Into The Generation Of CD4 Memory May Shape Future Vaccine Strategies For Influenza

Influenza viral evolution presents a formidable challenge to vaccination due to the virus’ ability to rapidly mutate to evade immune responses. Live influenza infections generate large and diverse CD4 effector T cell responses that yield highly protective, long-lasting CD4 T cell memory that can tar...

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Bibliographic Details
Main Authors: Priyadharshini eDevarajan, Bianca eBautista, Allen M Vong, Karl Kai McKinstry, Tara Marlene Strutt, Susan L Swain
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-04-01
Series:Frontiers in Immunology
Subjects:
Vaccination
influenza
CD4 T cells
cell-mediated immunity
memory checkpoint
late-antigen
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00136/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00136/full

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