Relationship of hypoxia-inducible factor 1α and p21<sup>WAF1/CIP1 </sup>expression to cell apoptosis and clinical outcome in patients with gastric cancer

Relationship of hypoxia-inducible factor 1α and p21<sup>WAF1/CIP1 </sup>expression to cell apoptosis and clinical outcome in patients with gastric cancer

<p>Abstract</p> <p>Background</p> <p>Hypoxia-inducible factor-1α (HIF-1α) plays an essential role in oxygen homeostasis. The expression of HIF-1α-inducible genes is associated with tumor progression. p21 mediates cell cycle arrest and is one of the downstream genes targ...

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Bibliographic Details
Main Authors: Oda Shinya, Kakeji Yoshihiro, Mizokami Ken, Maehara Yoshihiko
Format: Article
Language:English
Published: BMC 2006-12-01
Series:World Journal of Surgical Oncology
Online Access:http://www.wjso.com/content/4/1/94

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http://www.wjso.com/content/4/1/94

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