Whole-Exome Sequencing on Circulating Tumor Cells Explores Platinum-Drug Resistance Mutations in Advanced Non-small Cell Lung Cancer

Whole-Exome Sequencing on Circulating Tumor Cells Explores Platinum-Drug Resistance Mutations in Advanced Non-small Cell Lung Cancer

Circulating tumor cells (CTCs) have important applications in clinical practice on early tumor diagnosis, prognostic prediction, and treatment evaluation. Platinum-based chemotherapy is a fundamental treatment for non-small cell lung cancer (NSCLC) patients who are not suitable for targeted drug the...

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Bibliographic Details
Main Authors: Yuanyuan Chang, Yin Wang, Boyi Li, Xingzhong Lu, Ruiru Wang, Hui Li, Bo Yan, Aiqin Gu, Weimin Wang, Aimi Huang, Shuangxiu Wu, Rong Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Genetics
Subjects:
circulating tumor cells
drug resistance
non-small cell lung cancer
platinum-based chemotherapy
single cell–level WES
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.722078/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2021.722078/full

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