Cigarette Smoking Triggers Colitis by IFN-γ+ CD4+ T Cells

The increased incidence of Crohn’s disease in smokers has been recently reported, suggesting a strong association of cigarette smoke (CS) with colitis. However, the mechanism of the action of CS on colitis has not yet been explored. Here, we demonstrate that CS exposure is sufficient to induce colit...

Full description

Bibliographic Details
Main Authors: Gihyun Lee, Kyoung-Hwa Jung, Dasom Shin, Chanju Lee, Woogyeong Kim, Sujin Lee, Jinju Kim, Hyunsu Bae
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-10-01
Series:Frontiers in Immunology
Subjects:
Th1
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01344/full