Structural insights into the activity and regulation of human Josephin-2

The MJD family of human deubiquitinating enzymes contains four members: Ataxin-3, the ataxin-3-like protein (AT3L), Josephin-1, and Josephin-2. All share a conserved catalytic unit known as the Josephin domain. Ataxin-3 and AT3L also contain extensive regulatory regions that modulate their functions...

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Bibliographic Details
Main Authors: Kimberly C. Grasty, Stephen D. Weeks, Patrick J. Loll
Format: Article
Language:English
Published: Elsevier 2019-07-01
Series:Journal of Structural Biology: X
Online Access:http://www.sciencedirect.com/science/article/pii/S2590152419300091