TRAF6 and IRF7 control HIV replication in macrophages.

TRAF6 and IRF7 control HIV replication in macrophages.

The innate immune system recognizes virus infection and evokes antiviral responses which include producing type I interferons (IFNs). The induction of IFN provides a crucial mechanism of antiviral defense by upregulating interferon-stimulated genes (ISGs) that restrict viral replication. ISGs inhibi...

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Bibliographic Details
Main Authors: Mélissa Sirois, Lynda Robitaille, Robin Allary, Mohak Shah, Christopher H Woelk, Jérôme Estaquier, Jacques Corbeil
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3225375?pdf=render

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http://europepmc.org/articles/PMC3225375?pdf=render

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