Inhibition of Let7c microRNA is neuroprotective in a rat intracerebral hemorrhage model.

Inhibition of Let7c microRNA is neuroprotective in a rat intracerebral hemorrhage model.

Intracerebral hemorrhage (ICH) is a devastating neurological disease with a grave prognosis. We evaluated microRNA (miRNA) expression after ICH and evaluated Let7c as a therapeutic target. We harvested hemorrhagic brain 24 hours after collagenase induced ICH in the rat. Microarray analysis was perfo...

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Bibliographic Details
Main Authors: Jeong-Min Kim, Soon-Tae Lee, Kon Chu, Keun-Hwa Jung, Jin Hee Kim, Jung-Suk Yu, Soyun Kim, So Hee Kim, Dong-Kyu Park, Jangsup Moon, Jaejun Ban, Manho Kim, Sang Kun Lee, Jae-Kyu Roh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4068982?pdf=render

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http://europepmc.org/articles/PMC4068982?pdf=render

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