Exploring the Anti-quorum Sensing and Antibiofilm Efficacy of Phytol against Serratia marcescens Associated Acute Pyelonephritis Infection in Wistar Rats

Exploring the Anti-quorum Sensing and Antibiofilm Efficacy of Phytol against Serratia marcescens Associated Acute Pyelonephritis Infection in Wistar Rats

Quorum Sensing (QS) mechanism, a bacterial density-dependent gene expression system, governs the Serratia marcescens pathogenesis through the production of virulence factors and biofilm formation. The present study demonstrates the anti-quorum sensing (anti-QS), antibiofilm potential and in vivo pro...

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Bibliographic Details
Main Authors: Ramanathan Srinivasan, Ramar Mohankumar, Arunachalam Kannappan, Veeramani Karthick Raja, Govindaraju Archunan, Shunmugiah Karutha Pandian, Kandasamy Ruckmani, Arumugam Veera Ravi
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-12-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
acute pyelonephritis
antibiofilm
anti-inflammatory agents
anti-quorum sensing
phytol
Serratia marcescens
Online Access:http://journal.frontiersin.org/article/10.3389/fcimb.2017.00498/full

Internet

http://journal.frontiersin.org/article/10.3389/fcimb.2017.00498/full

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