Strengths and Weaknesses of the Current Strategies to Map and Characterize R-Loops

R-loops are evolutionarily conserved three-stranded structures that result from the formation of stable DNA:RNA hybrids in the genome. R-loops have attracted increasing interest in recent years as potent regulators of gene expression and genome stability. In particular, their strong association with...

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Bibliographic Details
Main Author: Vincent Vanoosthuyse
Format: Article
Language:English
Published: MDPI AG 2018-03-01
Series:Non-Coding RNA
Subjects:
Online Access:http://www.mdpi.com/2311-553X/4/2/9