Role of Lipopolysaccharide in Protecting OmpT from Autoproteolysis during In Vitro Refolding
Outer membrane protease (OmpT) is a 33.5 kDa aspartyl protease that cleaves at dibasic sites and is thought to function as a defense mechanism for <i>E. coli</i> against cationic antimicrobial peptides secreted by the host immune system. Despite carrying three dibasic sites in its own se...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-06-01
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Series: | Biomolecules |
Subjects: | |
Online Access: | https://www.mdpi.com/2218-273X/10/6/922 |