Evolutionary history of histone demethylase families: distinct evolutionary patterns suggest functional divergence
<p>Abstract</p> <p>Background</p> <p>Histone methylation can dramatically affect chromatin structure and gene expression and was considered irreversible until recent discoveries of two families of histone demethylases, the KDM1 (previously LSD1) and JmjC domain-containi...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2008-10-01
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| Series: | BMC Evolutionary Biology |
| Online Access: | http://www.biomedcentral.com/1471-2148/8/294 |