Crystal Structures of the 43 kDa ATPase Domain of <i>Xanthomonas Oryzae</i> pv. <i>Oryzae</i> Topoisomerase IV ParE Subunit and its Complex with Novobiocin
Topoisomerase IV, one of the best-established antibacterial targets, is an enzyme crucial for chromosome segregation and cell division by catalyzing changes in DNA topology through breaking and rejoining DNA. This enzyme functions as a heterotetramer consisting of two ParC and two ParE subunits. Ami...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-11-01
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Series: | Crystals |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4352/9/11/577 |