Pioglitazone treatment increases survival and prevents body weight loss in tumor-bearing animals: possible anti-cachectic effect.

Pioglitazone treatment increases survival and prevents body weight loss in tumor-bearing animals: possible anti-cachectic effect.

Cachexia is a multifactorial syndrome characterized by profound involuntary weight loss, fat depletion, skeletal muscle wasting, and asthenia; all symptoms are not entirely attributable to inadequate nutritional intake. Adipose tissue and skeletal muscle loss during cancer cachexia development has b...

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Bibliographic Details
Main Authors: Mércia Beluzi, Sidney B Peres, Felipe S Henriques, Rogério A L Sertié, Felipe O Franco, Kaltinaitis B Santos, Pâmela Knobl, Sandra Andreotti, Cláudio S Shida, Rodrigo X Neves, Stephen R Farmer, Marília Seelaender, Fábio B Lima, Miguel L Batista
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4373945?pdf=render

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http://europepmc.org/articles/PMC4373945?pdf=render

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