Modeling of Oxidized PTH (oxPTH) and Non-oxidized PTH (n-oxPTH) Receptor Binding and Relationship of Oxidized to Non-Oxidized PTH in Children with Chronic Renal Failure, Adult Patients on Hemodialysis and Kidney Transplant Recipients

Modeling of Oxidized PTH (oxPTH) and Non-oxidized PTH (n-oxPTH) Receptor Binding and Relationship of Oxidized to Non-Oxidized PTH in Children with Chronic Renal Failure, Adult Patients on Hemodialysis and Kidney Transplant Recipients

Background: The biological properties of oxidized and non-oxidized PTH are substantially different. Oxidized PTH (oxPTH) loses its PTH receptor-stimulating properties, whereas non-oxidized PTH (n-oxPTH) is a full agonist of the receptor. This was described in more than 20 well published studies in t...

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Bibliographic Details
Main Authors: Berthold Hocher, Dominik Oberthür, Torsten Slowinski, Uwe Querfeld, Franz Schaefer, Anke Doyon, Martin Tepel, Heinz J. Roth, Hans J. Grön, Christoph Reichetzeder, Christian Betzel, Franz P. Armbruster
Format: Article
Language:English
Published: Karger Publishers 2013-07-01
Series:Kidney & Blood Pressure Research
Subjects:
n-oxPTH
Chronic Renal Failure
Kidney Transplantation
Hemodialysis
Oxidation
PTH
Chronic Renal Failure in Children
Online Access:http://www.karger.com/Article/FullText/350149

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http://www.karger.com/Article/FullText/350149

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