Regulation and Role of GLI1 in Cutaneous Squamous Cell Carcinoma Pathogenesis

Regulation and Role of GLI1 in Cutaneous Squamous Cell Carcinoma Pathogenesis

Cutaneous squamous cell carcinoma (cSCC) is the second most common skin tumor in humans. Although current therapies are sufficient to clear the tumor in many cases, the overall risk of cSCC metastasis is still 5%. Alternative treatment options could help to overcome this situation. Here we focused o...

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Bibliographic Details
Main Authors: Joanna Pyczek, Natalia Khizanishvili, Maria Kuzyakova, Sebastian Zabel, Julia Bauer, Frauke Nitzki, Steffen Emmert, Michael P. Schön, Petra Boukamp, Hans-Ulrich Schildhaus, Anja Uhmann, Heidi Hahn
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-12-01
Series:Frontiers in Genetics
Subjects:
Hedgehog signaling
cutaneous squamous cell carcinoma
GLI1
epidermal growth factor receptor
ERK
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2019.01185/full

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https://www.frontiersin.org/article/10.3389/fgene.2019.01185/full

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