The quantitation of atorvastatin in human plasma by solid phase micro-extraction followed by LC-MS/MS and its application to pharmacokinetics study

The quantitation of atorvastatin in human plasma by solid phase micro-extraction followed by LC-MS/MS and its application to pharmacokinetics study

Determination of atorvastatin in human plasma using LC-MS/MS has been widely accepted as an effective methodowing to its practical applicability in routine drug analysis in pharmacokinetic and pharmacogenetic study. Nevertheless, themethod sensitivity can be compromised when limited sample volume is...

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Bibliographic Details
Main Authors: Pattarawit Rukthong, Polkit Sangvanich, Sarunyaporn Kitchaiya, Ekarat Jantratid, Korbtham Sathirakul
Format: Article
Language:English
Published: Prince of Songkla University 2013-02-01
Series:Songklanakarin Journal of Science and Technology (SJST)
Subjects:
atorvastatin
LC-MS/MS
plasma
solid phase micro-extraction
pharmacokinetics
Online Access:http://rdo.psu.ac.th/sjstweb/journal/35-1/35-1-41-50.pdf

Internet

http://rdo.psu.ac.th/sjstweb/journal/35-1/35-1-41-50.pdf

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